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As the dominant G-actin sequestering protein in mammalian cells, TB-500 binds globular actin with high affinity (Kd ~0.5 M) through a sophisticated triple-contact mechanism involving Lys-3, Lys-18, and Lys-38 residues, preventing spontaneous actin polymerization while maintaining a readily mobilizable reservoir for rapid cytoskeletal reorganization

Formulated with 64% Galactomyces Ferment Filtrate, this rich yet lightweight moisturizer replenishes hydration while improving tone and texture for visibly brighter, softer skin

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Purified water*, niacinamide (50,000 ppm), propanediol, glycerin*, 1,2-hexanediol*, glutathione* (5,000 ppm), arginine, adenosine, guava flower extract, basil leaf extract, lactobacillus ferment, guava leaf extract, turmeric root extract, yeast ferment, coral extract, fig fruit/leaf extract, broccoli extract, dipotassium glycyrrhizate, tomato extract, sodium hyaluronate, sodium hyaluronate crosspolymer, hydrolyzed hyaluronic acid, hyaluronic acid, potassium hyaluronate, hydrolyzed sodium hyaluronate, ceramide NP, panthenol, cy Anocobalamin, Tocopherol, Pyridoxine, Magnesium Ascorbyl Phosphate, Arbutin, Ferulic Acid, Isopropyl Myristate, Polyglyceryl-4 Caprate, Sodium Citrate, Dipropylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydroxyacetophenone, Meadowfoam Seed Oil, Xanthan Gum, Caprylyl Glycol, Butylene Glycol, Disodium EDTA, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Polyglyceryl-3 Methyl Glucose Distearate, Polyglyceryl-10 Stearate*, Caprylic/Capric Triglyceride, Arginine/Lysine Polypeptide*, Thioctic Acid, Fragrance

The activity and expression of glutathione transferases (GSTs) depend on several less-known endogenous and well-described exogenous factors, such as the deve...