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In addition, as demonstrated by growing research, non-obstructive coronary artery disease (NOCAD) is also quite common in ischemia or chest pain (CP) and has a significant financial impact [173,174,175]

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148 In addition to instigating the XBP1s-mediated transcriptional response, activated IRE1 also serves as a scaffolding protein that facilitates the activation of other signaling pathways

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