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It is important to note that there is evidence for this AOP primarily in fish studies, however there is no indication that this AOP would not be applicable to other species or life stages

The gap between results comes down to delivery mechanism

In the transmethylation reaction, S-adenosylhomocysteine (SAH) is produced with the participation of SAM

"Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial." Annals of Internal Medicine

J Biol Chem 286: 89778987, 2011 [DOI] [PMC free article] [PubMed] [Google Scholar] 101.Stanton RC
