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Some researchers suggest the reduction in the pineal glands output of melatonin is the reason why older adults may have more difficulty sleeping or may find their sleep rhythms are off, such as feeling sleepy during the day or awake at night

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A comprehensive review of opioid-induced hyperalgesia

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doi: 10.3389/fpsyt.2025.1505397 Received 02 October 2024 Accepted 05 February 2025 Published 21 February 2025 Volume 16 - 2025 Edited by Sergei V
