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Moreover, it has been proven that gorging induced by obvious hunger after zero-calorie fasting has a harmful effect on health, especially with respect to weight gain [23]
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One possible explanation for the clinical differences between RBD-PD and PD without RBD (non-RBD-PD) is the body-first and brain-first hypotheses of PD pathogenesis
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This study then compared fresh stem cells from a patients' own bone marrow mesenchymal stem cells and showed that these stem cells were abundant even in elderly patients and retained dramatic abilities to live, grow, proliferate, and differentiate into tissue-specific subtypes [36], plus these cells can build new tissue without causing an immune reaction (unlike foreign donor cells)

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With increasing research on MenSCs, the therapeutic potential of their paracrine mechanisms has been validated in various diseases
