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The optimal dose is the lowest dose that produces the desired clinical effect with acceptable tolerability

Vinogradov IV, Gamidov SI, Gabliya MY, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 227

(By contrast, plain Sterile Water for Injection has no preservative and must be used as a single dose.) The product label explicitly notes that the vial may be made to dilute or dissolve drugs for injection and is designed for repeated withdrawals

[Google Scholar] 15.Ahmad I, Hafeez A, Akhter N, Vaid FHM, Qadeer K
