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Adachi Y, Kato T, Yamada T, Murata D, Arai K, Stahelin RV, et al
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
Results from phase II clinical trials confirmed that canakinumab is safe and effectively targets IL-1 signaling, and yielded durable response in LR-MDS patients with single somatic driver mutation in TET2 or DNMT3A [256, 257]
The research continues to evolve, and I remain committed to staying at the forefront of these discoveries to better serve my patients and community
Maintenance dosing schedules are less often than the first doses, usually monthly
