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Alterations in intestinal microbiota have been shown to impair inflammatory cell function by disrupting the Th17/Treg axis following the depletion of butyrate- or short-chain fatty acid-producing bacteria

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Ginsenoside Rh2 impedes proliferation and migration and induces apoptosis by regulating NF-kappaB, MAPK, and PI3K/Akt/mTOR signaling pathways in osteosarcoma cells

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The newest generation agent, opicapone, is also a peripherally selective inhibitor

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Mitochondrion 11 , 207213 (2011)

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