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Phenolic compounds have a major role in plant cells, i.e., protecting cells from UV rays of sunlight and insect predators (producing annoying/toxic substances) and penetration of pathogens (fungi) in addition to attracting plant pollinators (143, 146)

This process leads to the activation of macrophages, the secretion of inflammatory factors, and ultimately, inflammation in cells such as Kupffer cells, as well as hepatocytes, which produce significant amounts of cytokine, particularly TNF- and IL-6 (Allam et al

Measurements of Hepatic mRNA Levels of Lipid Metabolism Genes by Real-Time PCR Liver tissues were collected for the expressions of genes related to lipid metabolism (24 h, 48 h) (n 3)