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Furthermore, IgD - CD27 + switched memory B cell counts seem to be more affected in CPs than IgD + CD27 + unswitched memory B cell counts ( Figures 6D, E )

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Pregnancy and lactation safety has not been systematically studied, and as with most cosmetic and research compounds lacking definitive pregnancy safety data, conservative practice typically suggests avoiding use during pregnancy unless clearly needed, though the natural occurrence of GHK-Cu in the body and minimal systemic absorption from topical use suggest risk is likely to be low