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Moreover, Ab was able to inhibit the production of ROS by macrophages stimulated in vitro with tBHP, and also tBHP-induced DNA damage in human PBMC

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Longevity Studies: Studies in animals have shown that spermidine may can extend lifespan and improve healthspan, making it an area of interest for longevity researchers.(3) DNA and Cellular Stability: Spermidine supports cellular homeostasis and DNA repair, which aligns with Sinclair's focus on protecting and restoring the epigenome

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A recent study has concluded that low molecular mass systemic thiols might play a role in the inflammatory and oxidative stress pathways involved in both chronic obstructive pulmonary disease (COPD) and cardiovascular disease [91]

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Wood ZA, Poole LB, Karplus PA

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