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[Abstract] Ovarian cancer ID8 syngeneic model testing fluoxetine effect, Fluoxetine treatment (20 mg/kg over drinking water starting 7 days before first chemotherapy and continued until harvest), Cisplatin (5 mg/kg, twice/week, intraperitoneal injection in indicated time windows)

These above conditions frequently overlap and interact, requiring a nuanced and multidisciplinary approach to care

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In the skeletal muscle microcirculation, HS increases reactive oxygen species (ROS) production via increased NADPH and xanthine oxidase activity [25] and impairs antioxidant defenses by decreasing Cu/Zn superoxide dismutase (SOD) activity

Impaired defense mechanisms following IPH might limit the clearance of extracellular Hb and heme from the atherosclerotic plaque thereby this could be a new etiopathogenic factor to address in details in the future