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10.1523/JNEUROSCI.2084-10.2010 J Neurosci

4.1 Clinical relevance of the CLP model The CLP model was selected for its unique ability to recapitulate core clinical features of SAE: polymicrobial sepsis, hippocampal neurodegeneration, and chronic cognitive impairment (Yin et al., 2023)

Additionally, our study found that the abundance of Bacteroidota was higher in the ESC group compared to the other two groups, while Firmicutes was less abundant
An increase in blood bacterial DNA concentration has been observed, which was dependent on blood low-density lipoprotein cholesterol elevation in the myocardial infarction group
