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Description
Unlike GLP-1 agonists that reduce appetite or growth hormone peptides that stimulate lipolysis, the compound addresses fat metabolism at the enzymatic level: it removes the molecular governor that locks adipocytes into a low-energy-expenditure state, potentially restoring normal metabolic function in fat tissue where NNMT is overexpressed
doi: 10.1016/s0753-3322(03)00043-x 280 TrachoothamD.LuW.OgasawaraM
Cell Metabolism
Bratisl Med J Bratisl Lek Listy 2021;122:200205 10
10.1186/s12974-019-1581-6 329 TsujimotoS.YanagimachiM.TanoshimaR.UrayamaK
