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10.1080/10408398.2021.1917508 36 ChenM.WangR.WangT

Neither the NAD+ cohort nor the placebo (saline) cohort experienced any negative side effects throughout the 6 hour infusion (10) At 8 hours following the start of the NAD+ infusion, it was shown that the NAD+ group had significant declines in the liver function enzymes gamma glutamyl transferase, lactate dehydrogenase, and aspartate aminotransferase as well as a large increase in plasma bilirubin (10)

This observation is consistent with the microscopic analysis performed (Fig

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