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For vitamin D, as an example, the AI (RDA) in Japan is only 8.5 g/day (340 IU/day) for adults, whereas in the US the RDA is 600 IU

Those with severe deficiencies may receive more frequent Optimal B12 injection dosage for adults at first before tapering frequency

Biochimica et Biophysica Acta (BBA)-Bioenergetics 1847(11):14341447

In addition to the hormones GIP and glucagon, other hormones such as estrogen, peptide tyrosine tyrosine (PYY), gastrin, xenin, and fibroblast growth factor 21 can be good candidates to pair with GLP-1 and create dual agonists that have anti-diabetic and anti-obesity effects

Statements not evaluated by the FDA