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Inhibitory effects of astaxanthin on postovulatory porcine oocyte aging in vitro

The ALOX family can mediate PUFAs peroxidation to generate AA/AdA-PE-OOHs, thereby triggering ferroptosis (Lei et al., 2019)

AP: Writing review & editing, Conceptualization, Resources, Supervision, Writing original draft

Figure 2 3.1.1 Preclinical foundations and mechanisms Preclinical studies in animal models have established the foundational rationale for this approach

391,392 In an experimental study evaluating the effects of KGF therapy on thymic architecture and T cell immune reconstitution following myeloablative total body irradiation and autologous peripheral blood progenitor cell (PBPC) transplantation in healthy rhesus macaques, KGF treatment significantly increased de novo T cell production and the recovery of nave T cells