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People with chronic fatigue or anemia require weekly to monthly injections of vitamin B12 usually because the oral form is not dependable
Neurodegenerative diseases (NDDs) are related with the presence of abnormal protein folding, aggregation and deposition in the brain, which lead to alterations in neural functioning, and ultimately, neural cell death (66)

doi: 10.1016/j.cbi.2023.110632 167

Homocarnosine concentration of the autopsied brain ranges from 0.4 mmol/kg in the corpus callosum and temporal cortex to 1.0 mmol/kg in the thalamus and basal ganglia and varies independently of GABA concentrations 120
doi: 10.1513/pats.200807-069TH