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In PTPSD, 13/26 cMRI and 3/5 cCT were normal

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B12 is water-soluble, meaning excess amounts are safely excreted through urine rather than accumulating in your body, making toxicity extremely rare even at high supplement doses

Given that distinct microbial derivatives act through unique molecular targets and pathways to regulate the enteric nervous system (ENS), this review adopts a categorical approach to elucidate the mechanisms underlying their crosstalk more clearly within the gut microbiota-ENS axis ( Figure 3 )

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