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In PTPSD, 13/26 cMRI and 3/5 cCT were normal

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B12 is water-soluble, meaning excess amounts are safely excreted through urine rather than accumulating in your body, making toxicity extremely rare even at high supplement doses

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Given that distinct microbial derivatives act through unique molecular targets and pathways to regulate the enteric nervous system (ENS), this review adopts a categorical approach to elucidate the mechanisms underlying their crosstalk more clearly within the gut microbiota-ENS axis ( Figure 3 )

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