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Tirzepatide has been approved for T2D management - the mean HbA1c reduction in SURPASS programme ranged between 1.9 and 2.6% across the trials and 4069% of participants achieved 10% WL with the higher doses (10 and 15 mg), despite that there was no additional support for lifestyle intervention [16, 43]

DOI: 10.1210/mend.10.8.8843412 Chen, J.D., Umesono, K., Evans, R.M

Pellegrini C, Navab N, Kazi A

48 These cells were subsequently reinfused into patients to evaluate their clinical efficacy and establish the safety profile of these stromal cells