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The Bottom Line Ipamorelin is a pentapeptide GH secretagogue that activates the GHS-R1a (ghrelin) receptor to release growth hormone without stimulating cortisol, ACTH, or prolactin, a selectivity profile documented at doses 200-fold above its effective GH-releasing dose

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Up-regulation of CX3CL1 via nuclear factor-b-dependent histone acetylation is involved in paclitaxel-induced peripheral neuropathy

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