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The genome also harbors a number of genes, annotated as dehydrogenases, oxidoreductases and oxidases for the possible metabolism of hydrolyzed side-chain alcohol, besides several gene clusters encoding for -oxidation pathway enzymes (Additional file 8: Table S3)

Membranes were probed overnight at 4 C with primary antibodies against p-c-Met (3077 T, Cell signaling), c-Met (8198 S, Cell signaling), p-AKT (AF0016, affinity), AKT (GR100134-1, abcam), p-ERK (AF1015, affinity), ERK (4695 T, Cell signaling), GAPDH (10494-1-AP, proteintech), p-TRKB (4603 T, Cell signaling), CyclinD1 (26939-1-AP, proteintech), cleaved caspase-3 (9661 L, Cell signaling), caspase-3 (66470-2-Ig, proteintech), N-cadherin (22018-1-ap, proteintech), E-cadherin (AF0138, Beyotime), -actin (A5441, Sigma), AXL (4977, CST), p-MER (AF8443, affinity), P-AXL (334580, abmart), NF-KB (10745-1-AP, proteintech), p-ALK (3341 S, CST), Ki67 (27309-1-AP, proteintech)

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A deficiency in Vitamin B12 can cause fatigue and sluggishness, so supplementing with B12 can help increase energy and combat tiredness, which is particularly useful for those on calorie-restricted diets

However, if you do find yourself deficient in vitamin B12, there is something you can do to improve it