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Current studies have revealed a strong link between ferroptosis and the GSH system, which has become a hotspot in the field of CVDs

doi: 102

Pairing glutathione with Vitamin C actively recycles it into its reduced form, extending its antioxidant effect at the cellular level

Drug Metab Rev 1998, 30 (2), 245275

Altogether, the GPx enzyme family exemplifies evolutionary adaptation to oxidative stress, with enzymatic diversity and specialization enabling sophisticated cellular protection mechanisms vital for life in an oxygen-rich environment [11]
