can glutamate make glutathione SYNTHESIS Stimulation of de novo glutathione
Description
Enzyme Cofactor: Supports antioxidant and detox pathways through enzymes such as glutathione peroxidases and glutathione S-transferases
The deletion of GCS1 , an ortholog of mammalian ArfGAP1, was originally identified as a suppressor of human LRRK2-induced cellular toxicity in yeast (Xiong et al., 2010)
1 2 "Redox regulation of enzymes involved in sulfate assimilation and in the synthesis of sulfur-containing amino acids and glutathione in plants"
10.1098/rsos.160850 12 ArtuncF.RislerT
Gomes HIO, Martins CSM, Prior JAV
