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NBCs Kate Snow reports.

Example Dose (10 mg)

* Bio-GEE : biotinylated glutathione ethyl ester DTT : 1,4-dithiothreitol ETC : electron transport chain GSH : reduced glutathione GSSG : oxidized glutathione LDH : lactate dehydrogenase LPS : lipopolysaccharide MitoCDNB : Mitochondrially-targeted 1-chloro-2,4-dinitrobenzene NEM : N-ethylmaleimide OGDHC : 2-oxoglutarate dehydrogenase complex PDC : pyruvate dehydrogenase complex PDCE2 : PDC E2 component PDCE3 : PDC E3 component ROS : reactive oxygen species SDS-PAGE : sodium dodecyl sulfate-polyacrylamide gel electrophoresis TLR : toll-like receptor

Dihexa is an angiotensin IV derivative peptide that exhibits strong affinity for hepatocyte growth factor (HGF) and activates the HGF/c-Met signaling pathway.

Using an untargeted NMR-based metabolomics approach combined with multivariate and statistical analyses, we identified significant metabolic alterations and assessed their diagnostic potential