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Aesthetically over-injection of cheeks can sometimes make temples look hollow even if they are not, but Botox isnt causing the fat or muscle in the temples to prematurely wane

10.1128/AEM.00589-08

[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Raleigh DR, Marchiando AM, Zhang Y, Shen L, Sasaki H, Wang Y, Long M, Turner JR, Omary MB

Copper can enhance expression of MMP-1, an enzyme that breaks down collagen
