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The clinical significance of the VMAT transporters is evidenced by the fact that variants in VMAT1 have been found to be associated with susceptibility for schizophrenia and bipolar depression

[9] The results indicate that some inherited polymorphic variations in NER genes may result in predisposition to lung cancer, and potentially other cancer states

R.YuY.PriceA.JoshiS.RoyA.et al (2022)

This pathway is controlled by GBE [2325]

Thus, the monosaccharides fructose, galactose, and ribose join upstream in the glycolytic pathway of cancer cells that express suitable GLUTs, kinases, or other enzymes favoring uridine catabolism