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Eisenberg L, Eisenberg-Bord M, Eisenberg-Lerner A, Sagi-Eisenberg R

Utomo, A

NMDA receptor activation elevates intracellular Ca 2+ , triggering NADPH-OX-mediated O production and mitochondrial electron leakage

Among the various regulatory factors, peroxisome proliferator-activated receptor (PPAR) coactivator 1 (PCG-1), the master regulator of mitochondrial biogenesis, emerges as an important component involved in the defective mitochondrial biogenesis in CKD (Sharma et al., 2013
