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Evidence that the pathway can work in an integrated fashion came from the effects of added oxidants on ascorbate and glutathione in purified chloroplasts (Law et al

High homocysteine concentrations may promote the development of atherosclerosis (atherogenesis) and thrombogenesis via mechanisms involving oxidative stress and endothelial dysfunction, inflammation, abnormal blood coagulation, and disordered lipid metabolism (reviewed in 35)

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Science 303 , 12011204 (2004)

Oral cancer refers to cancers that develop in the mouth, including the lips, tongue, cheeks, gums, floor of the mouth, and roof of the mouth