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Moreover, phospho-BCL-XL (Ser62) stabilizes G2 arrest by binding to and co-localizing with Cdk1 (cdc2) in nucleolar structures to avoid rapid nucleolar disassembly associated with mitosis onset, playing an unexpected role in the G2 phase checkpoint downstream of DNA damage distinct from its anti-apoptotic function 22

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The institute also acts as a referral centre for skin cancer patients from all over the Western Cape and comprises a multidisciplinary team of specialists providing patients with expert and evidence-based care

1996 Mar;44(3):311-6

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Matsufuji Y., Yamamoto K., Yamauchi K., Mitsunaga T., Hayakawa T., Nakagawa T