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Nephrotoxicity in the experimental and the clinical situation, Dordrecht, Boston, Lancaster, Martinus Nijhoff Publishers, pp

This appears to be due to loss of CSF-1 release in the ENS leading to loss of bone morphogenic protein-2 because of reduced macrophage numbers and a breakdown in the normal reciprocal regulatory state (327)

These occur because vitamin B12 is essential for maintaining the protective sheath around nerves

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Notably, respiratory viruses including SARS-CoV can induce the exacerbated activation of NF-B, leading to lung inflammatory immunopathology (64, 65)
