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Carcinogenesis 27(10):20382046 Huang TY, Chang WC, Wang MY, Yang YR, Hsu YC (2012) Effect of sulforaphane on growth inhibition in human brain malignant glioma GBM 8401 cells by means of mitochondrial-and MEK/ERK-mediated apoptosis pathway

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For example, in the case of AD, noticeably low plasma BDNF can occur up to 10 years before the onset of clinical symptoms and correlates with hippocampal atrophy, as observed in standard structural MRI imaging