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These adverse experiences were first studied by the CDC and the Kaiser Center in 1995 in the critically important Kaiser ACE Study, which connected the experience of ACEs to later poor mental and physical health outcomes

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However, the effects of anti-angiogenic agents administrated as monotherapy in cancer patients during clinical trials often failed to show significant survival benefits

acknowledges travel grants from the EMBO (scientific exchange grant number 9591) and the Universit Grenoble Alpes for a 1-month stay at the SACLA (Research Support Program for Graduate Students)

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