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Description
Pooled data were homogenous under a fixed effect model (p = 0.43, I = 0%), But the reduction in the rate of mechanical ventilation in the intervention group was statistically nonsignificant (pooled risk ratio, 0.71

Oxidative stress disrupts mitochondrial function by increasing reactive oxygen species (ROS) beyond normal levels
doi: 10.1016/j.bmc.2008.08.009

Ice crystal formation physically damages the peptide structure, creating aggregation and reducing biological activity

And that choice can seem risky because if we haven't done it before, it goes against every
