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In recent years, scientific interest focusing on the identification of SIRT1 modulators has led to the discovery of novel small molecules targeting SIRT1 activity

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Open Forum Infect Dis (2020) 7(10):ofaa407

The citric acid cycle includes a series of redox reactions in mitochondria

Fungal and Parasitic Triggers Even eukaryotic pathogens can trigger EBV: Plasmodium falciparum , the parasite responsible for malaria, can reactivate EBV through surface protein interactions Aspergillus flavus , a fungus that produces aflatoxins, can trigger EBV reactivation through toxic metabolites This multi-kingdom involvement highlights the complexity of EBV interactions with our microbiome and other pathogens