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Description
Within the gut UDCA bids to and activates the bile acid receptor, G-protein coupled bile acid receptor 1, GPBAR1 (originally identified as TGR5 and also known as GPR131) to enhance the expression of the proglucagon (GCG) gene in enteroendocrine L-cells resulting in increased production and release of GLP-1
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Retatrutide Mechanism and Early Response Signals Retatrutide acts as a triple receptor agonist, activating GLP-1, GIP, and glucagon pathways simultaneously
Ann Nutr Metab
Free Radic Biol Med [Internet], 72 (2014), pp
