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It provides the main redox buffer for cells and as such has been implicated in the formation of native disulphide bonds

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Endoplasmic reticulum stress (ERS) dynamically regulates cell fate decisions within the tumor microenvironment (TME) through the PERK, IRE1, and ATF6 pathways of the unfolded protein response (UPR), forming an ERS-Death Axis interconnected with apoptosis, autophagy, pyroptosis, and ferroptosis

Conclusion These findings highlight the activation of native plant beneficial soil microbes as a viable strategy to mitigate co-contamination and enhance grain safety in Cd-contaminated alkaline soils