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Research interest in the AngIV/AT4 receptor system was further encouraged by the finding that AT1 and AT2 receptor antagonists failed to block learning and memory tasks in animal models [70]

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The evidence of new bone formation covered a smaller area of the bone marrow, at the expense of the formation of cortical bone in the treated animals compared to the cortex in the control animals

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Activation of the BDNF pathway is well-known to increase dendritic spine growth and axonal connectivity, both of which are crucial mechanistic underpinnings of learning