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This systemic effect may explain why users sometimes report benefits beyond the specific area being treated

Diclofenac and eugenol hybrid with enhanced anti-inflammatory activity through activating HO-1 and inhibiting NF-B pathway in vitro and in vivo

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Intervertebral disc degeneration (IDD) is one of the primary causes of LBP (Fontana et al., 2015

This pathway has been implicated in several diseases including multiple types of cancers and cardiovascular diseases (178, 179)