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293 Interleukin-1 receptor-associated kinase 1/4 (IRAK1/4) is the main kinase in the TLR-mediated pathway, and inhibition of IRAK1/4 can block the TLR4/NF-B pathway and reduce intestinal inflammation

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The use of ZnPPIX, an HO1 inhibitor, significantly reduces BACH1's expression in an FBXO22dependent manner to inhibit lung cancer metastasis
