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However, the major receptor for the mitogenic, angiogenic and vascular permeability enhancing effects of VEGF is VEGFR-2 12

Here, we discuss about how pathogens have adapted their physiology to actively exploit the metabolic substrates generated by a robust inflammatory response, how they specifically modulate host metabolism to dampen the immune response, and how sensing the metabolic state of the local environment provides important cues to the bacterium regarding both the anatomical site of infection and the immune status of the area

These advancements suggest that artemisinin, when delivered through optimized drug delivery systems, holds great promise as a more effective treatment for a variety of cancers

In: Mukherjee, B
