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It coordinates virulence through the chemical-based communication mechanism called quorum-sensing (QS) 2

Zinc inhibits calcium-mediated and nitric oxide-mediated ion secretion in human enterocytes

Comparatively, there is a relatively higher risk for viruses to develop resistance as compared to AVPs designed to target the host cell proteins [62] due to the fact that a high rate of mutations may occur in the viral genome [57]

This multifactorial assault on glutathione homeostasis creates a compelling rationale for exogenous support, particularly through delivery methods that ensure reliable tissue concentrations

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