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Description
This prospective, phase IV study used an integrated genomic analysis to identify markers associated with 1-month change in IGF-I (IGF-I) following initiation of recombinant human (r-h)GH therapy in treatment-nave children with GH deficiency (GHD) (n=166) or Turner syndrome (TS) (n=147)

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Cells characterized by rapid division (epithelial cells, bone marrow, myeloid cells) appear to have the greatest requirement for cyanocobalamin
