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Nature 421 , 844848 (2003)

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This method comprises administering to the subject an effective amount of a ferroptosis inhibitor, which comprises a compound having the structure of formula (IV): R 1 is selected from the group consisting of aryl, C 1-6 alkyl-aryl, and C 3-10 carbocycle, wherein the aryl, C 1-6 alkyl-aryl, and C 3-10 carbocycle may be optionally substituted with an atom or a group selected from the group consisting of halo, deuterium, C 1-6 alkyl, CF 3 , and combinations thereof

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