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Most of these reactions occur within several days of initiation of therapy
14 - 21 Consequently, as we emphasized, 4 since the original organoprotective/healing intention of stress coping response 22 confronts with unsuccessful realization by the Selyes first mediator in stress response, 25 that integrative mediator that integrates the adaptive bodily response to stress, remains obscured in the highly sophisticated latter Selyes stress concept presentation

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