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Intact antibodies and other larger molecules, in contrast, are physically unable to enter the conduits, and they are thought to be transported to the LNs only within migratory DCs after proteolytic degradation

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Actin is a fundamental protein that forms the cytoskeleton of cells

Therefore, polymer micelles present an ideal carrier molecule for active or passive targeted drug delivery as they improve the therapeutic index while reducing toxic side effects (4044)

10.1016/s0149-2918(03)90096-8 [DOI] [PubMed] [Google Scholar] Bor M