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Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology

Here, we show that the ligand-induced PEPR1 endocytosis depends on its kinase activity and requires BAK1 C-terminal tail phosphorylation, which is equally indispensable for immune signaling and BAK1 internalization

Additional studies will be necessary to fully understand the biochemistry and the exact catalytic cascade of FSP1

This patient's distant spread to the liver and lungs involves venous pathways rather than arterial vessels

In this study, we identified that urinary prolegumain levels positively correlated with the malignant characteristics of ccRCC