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instead, they decrease neuronal survival

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It has been suggested that exogenous oxidative stress reduces the expression of nuclear RanGTPase-activating protein, which is essential for the nuclear import of cargo proteins and re-localisation of importin-, resulting in impaired nuclear import, and thereby the reduced GR function and corticosteroid responsiveness seen in patients with COPD [44]

Specifically, under section 1886(d)(3)(E) of the Act, the Secretary estimates, from time to time, the proportion of payments that are labor-related and adjusts the proportion (as estimated by the Secretary from time to time) of hospitals' costs which are attributable to wages and wage-related costs of the DRG prospective payment rates