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Presumably, these variants reduced the coupling efficiency of mitochondrial OXPHOS (loose coupling), resulting in an increase in the number of calories burned by the mitochondria to generate the ATP required to perform work

Accessed Aug 2020 Daura X, Gademann K, Jaun B, Seebach D, van Gunsteren WF, Mark AE (1999) Peptide folding: when simulation meets experiment

Current and experimental treatments of Parkinson disease: a guide for neuroscientists

Monoamine transporter inhibitors and norepinephrine reduce dopamine-dependent iron toxicity in cells derived from the substantia nigra

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