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The activity of NRF2 is primarily regulated post-translationally through its interaction with Kelch-like ECH-associated protein 1 (KEAP1), a crucial regulator of NRF2 under basal redox conditions

[DOI] [PMC free article] [PubMed] [Google Scholar] Nakamichi N, Nakayama K, Ishimoto T, Masuo Y, Wakayama T, Sekiguchi H, Sutoh K, Usumi K, Iseki S, Kato Y

In the Diabetes Reduction Assessment with Ramipril and Rosiglitazone Medication (DREAM) research, rosiglitazone reduced T2DM and improved normoglycemia in IFG patients